7 results
Management of Diabetes Mellitus in Patients With CKD

1. Monitor for changes in BP, serum creatinine, &
Management of Diabetes ... creatinine, & serum K+ ... patients with Type 1 diabetes ... or Type 2 diabetes ... #Diabetes #CKD #
Estimating the Total Daily Dose (TDD) of Insulin: Weight-Based Dosing
TDD in units of insulin = N
(stage IV or V CKD ... including most type 1 diabetics ... including most 2 diabetics ... endocrinology #diabetes ... #DM2
Sulfonylureas - Pharmacology Summary
Mechanisms of Action: Binds to the ATP-sensitive potassium channel in pancreatic beta cells,
Sulfonylureas - Pharmacology ... cells, triggering insulin ... contraindicated in CKD ... #Summary #DM2 # ... diabetes #endocrinology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia: • CKD ... Poorly controlled DM ... • NSAIDs • ACE ... (Uncontrolled diabetes ... paralysis - Insulin
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia: • CKD ... Poorly controlled DM ... • NSAIDs • ACE ... (Uncontrolled diabetes ... paralysis - Insulin
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
, ACEi/ARBs, NSAIDs ... transfusions), ↓insulin ... (DM, DKA, octreotide ... VBG (acidosis), CK ... Treatments: • Insulin
Veltassa (Patiromer) 
MECHANISM: Potassium Binder 
INDICATION: Treatment of Hyperkalemia 
FORMULATION: Powder for oral suspension 
DOSING: 8.4
needed, based on K ... patients with CKD ... , HF, or diabetes ... ACE inhibitors, ... #Hyperkalemia #Pharmacology