5 results
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Side Effects: Edema ... also binds magnesium ... nonspecifically binds ... #medications #pharmacology ... table #comparison #binders
Veltassa (Patiromer) 
MECHANISM: Potassium Binder 
INDICATION: Treatment of Hyperkalemia 
FORMULATION: Powder for oral suspension 
DOSING: 8.4
MECHANISM: Potassium Binder ... needed, based on K ... patients with CKD ... #KBinder #Hyperkalemia ... #Pharmacology
Effects of Prostaglandins and NSAIDs on the Kidney
Effects of Prostaglandins on the Kidney:
 • The vasodilatory
Thus, under conditions ... retention of Na, K ... is increased in CKD ... prolonged NSAID use in CKD ... renal #nephrology #pharmacology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... VBG (acidosis), CK ... - Diuresis (hypervolemia ... caution in HTN & edema ... #Hyperkalemia
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison

Composition of LR:
 • Sodium 130 mEq/L
 •
trial • Minimal K ... Is Dangerous in Hyperkalemia ... • Increases Edema ... volume - increased edema ... NS #comparison #pharmacology