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nephrology potassium diagnosis comparison differential high medications table binders binding diuresis diuretics effects excretion lactated lr management normal ns renal
Potassium-Binding Agents to Treat Hyperkalemia Sodium zirconium cyclosilicate (Lokelma): • Mechanism: Preferentially captures K in exchange for
desired serum K ... Side Effects: Edema ... constipation, diarrhea, nausea ... ); nausea, vomiting ... #medications #pharmacology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... : • CKD • Poorly ... transfusion • HTN and edema ... • Digoxin • K ... differential #diagnosis #causes
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... : • CKD • Poorly ... transfusion • HTN and edema ... • Digoxin • K ... differential #diagnosis #causes
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... Weakness, cramping, nausea ... VBG (acidosis), CK ... only if no clear cause ... caution in HTN & edema
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison Composition of LR: • Sodium 130 mEq/L •
trial • Minimal K ... Is Dangerous in Hyperkalemia ... shift • Saline Causes ... • Saline May Cause ... NS #comparison #pharmacology
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
Inhibitors of Na+K+ ... Hyponatremia • Hypercalcemia ... Kidney stones caused ... Epithelial Channels (K+ ... Diuresis #Nephrology #Pharmacology
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