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causes diagnosis differential endocrinology nephrology high hyperkalemia metformin potassium summary acei ada algorithm arb based dosing egfr estimation kdigo kidneydisease
Estimating the Total Daily Dose (TDD) of Insulin: Weight-Based Dosing TDD in units of insulin = N
(stage IV or V CKD ... including most type 1 diabetics ... including most 2 diabetics ... endocrinology #diabetes ... #DM2
Sulfonylureas - Pharmacology Summary Mechanisms of Action: Binds to the ATP-sensitive potassium channel in pancreatic beta cells,
Sulfonylureas - Pharmacology ... cells, triggering insulin ... contraindicated in CKD ... #Summary #DM2 # ... diabetes #endocrinology
Metformin Pharmacology Summary Mechanisms of Action: • Suppresses gluconeogenesis by the liver • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... • Increases insulin-mediated ... Contraindications: • Chronic ... #Summary #DM2 # ... diabetes #endocrinology
Management of Diabetes Mellitus in Patients With CKD 1. Monitor for changes in BP, serum creatinine, &
Management of Diabetes ... patients with Type 1 diabetes ... or Type 2 diabetes ... #Diabetes #CKD # ... #KDIGO #eGFR #Insulin
Causes of Chronic Kidney Disease - Differential Diagnosis Algorithm Decreased kidney function (eGFR < 60 ml/min/1.73 m2)
Causes of Chronic ... 60 ml/min/1.73 m2 ... Proteinuria) • Diabetes ... ) • Multiple myeloma ... Hyperphosphatemia #CKD
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia: • CKD ... Poorly controlled DM ... trauma - Ischemic colonic ... (Uncontrolled diabetes ... paralysis - Insulin
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia: • CKD ... Poorly controlled DM ... trauma - Ischemic colonic ... (Uncontrolled diabetes ... paralysis - Insulin
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