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management oncology acs allergic apml barre criteria dermatology differential differentiation gbs guillain kounis leukostasis lysis neurology signs sweet tls tryptase
Clinical manifestations of anaphylaxis. Neurological (<15%): Dizziness, syncope, seizures, Confusion, impending doom. headache Angioedema: Lips, tongue, orbit,
arrest, Kounis syndrome ... arrest GI (>40%): Nausea ... #signs #symptoms ... #diagnosis #criteria ... #allergy
Approach to Elevated Tryptase - Differential Diagnosis Framework The DDx of elevated tryptase can be broken down
- Differential Diagnosis ... : • Anaphylaxis ... cell activation syndrome ... #Differential #Diagnosis ... #hematology #allergy
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... : • Pathophysiology ... #TLS #diagnosis ... #management #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... : >3 symptoms, or ... PE, DAH, CHF, Anaphylaxis ... #management #hematology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
development of skin symptoms ... Causes: - Idiopathic ... , breast CA - Hematologic ... - Allergic contact ... #diagnosis #dermatology
Kounis Syndrome Acute coronary syndrome (symptoms such as chest pain relating to reduced blood flow to the
(symptoms such ... to the heart) caused ... #Diagnosis #Kounis ... #Syndrome #Allergic ... #ACS #Anaphylaxis
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Guillain-Barré Syndrome ... Incidence: 1 to 2 cases ... albuminocytologic dissociation ... than one after symptom ... the underlying pathophysiology
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