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diagnosis rheumatology differential vasculitis management erythematosus sle algorithm systemic treatment ana antinuclear cardiology causes classification glomerulonephritis guidelines nephrology table antibodies
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Antibody) and ANCA ... ) • Systemic lupus ... 80-90%) > MPO - ANCA ... MPO: 75-80% - ANCA ... Antinuclear #Antibody #ANCA
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Rheumatology • Lupus ... glycoprotein I (ß2GP), Lupus ... Polymerase Ill • ANCA ... Vasculitis: P-ANCA ... perinuclear), C-ANCA
Approach to managing Glomerulonephritis (GN) in children. ANCA, antineutrophil cytoplasmic antibodies; c-ANCA, cytoplasmic antineutrophil cytoplasmic antibodies;
ANCA, antineutrophil ... antibodies; c-ANCA ... hypertension; p-ANCA ... SLE, systemic lupus
Glomerulonephritis - Differential Diagnosis Framework ANCA: • C-ANCA: GPA (Wegener's) • P-ANCA: Microscopic Polyangiitis, Eosinophilic GPA (Churg
Diagnosis Framework ANCA ... : • C-ANCA: GPA ... Wegener's) • P-ANCA ... Membranoproliferative • ↓C4: Lupus
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Associated - ANCA ... Granulomas - ANCA ... inflammation Others: • Lupus ... disease): • Takayasu ... such as systemic lupus
Vasculitis Management - ACR/VF 2021 Guidelines for Treatment & Management • Giant Cell Arteritis (GCA) •
Arteritis (GCA) • Takayasu's ... Management #Treatment #ACR2021
2021 ACR/VF Guidelines for Management of Takayasu Arteritis (TAK) #Takayasu #Arteritis #TAK #ACR2021 #Management #rheumatology #algorithm #vasculitis
Management of Takayasu ... Arteritis (TAK) #Takayasu ... Arteritis #TAK #ACR2021
Granulomatosis with Polyangiitis (GPA) and Microscopic Polyangiitis (MPA) - ANCA Vasculitis Management Algorithm - ACR/VF 2021
Polyangiitis (MPA) - ANCA ... Polyangiitis #MPA #ANCA ... Management #Treatment #ACR2021
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pauci-Immune: - ANCA-positive ... polyangiitis) - ANCA-negative ... Complex: Systemic lupus ... testing: anti-ANCA ... , anti-GBM ab, ANA
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Post-strep GN, Lupus ... Negative IF): • PR3-ANCA ... (C-ANCA): GPA > ... > eGPA • MPO-ANCA ... (P-ANCA): eGPA,
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