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clinical diagnosis hepatology pathophysiology bloodsmear codocytes pathology pathophys acanthocytes acetaminophen alkphos antimda5 antimda5dm apap asplenic astalt autoimmune bilirubin bite blister
Several artifacts can cause significant and potentially misleading alterations to measured RBC parameters: 1. Old samples
Dacrocytes, #Teardrops #TargetCells ... BurrCells #Bite #Keratocyte
Post-splenectomy blood smear demonstrating Howell-Jolly bodies and target cells. #Clinical #Pathology #BloodSmear #HowellJollyBodies #TargetCells #Splenectomy #Asplenic
HowellJollyBodies #TargetCells
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism AST and ALT: • AST: liver
Synthesis: in hepatocyte ... accumulation in hepatocyte ... from albumin upon hepatocyte ... conjugation in hepatocyte ... reuptake into hepatocyte
Pathology - Hepatocyte Pigments Lipofuschin (H&E) Alpha-I-antitrypsin globules (PAS-D) Mallory's hyaline / Mallory Denk Bodies Giant Mitochondria
Pathology - Hepatocyte ... bilirubinostasis (H&E) #Hepatocyte
Codocytes (Target cells) - Two target cells are seen in the left photo and one in
Smear #Codocytes #TargetCells
Pemphigus vulgaris (PV) is an autoimmune, intraepithelial, blistering disease affecting the skin and mucous membranes. It
autoantibodies against keratinocyte ... enzymes that mediate keratinocyte
N-Acetyl Cysteine (NAC) Therapy Mechanism of Action: The non-toxic route of APAP metabolism gets saturated in
the extent of hepatocyte
Classification of Jaundice Unconjugated hyperbilirubinemia (predominantly indirect bilirubin) • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
epithelial and hepatocyte
The Mechanism of Small Interfering RNA (siRNA) Therapy. Synthetic double-stranded RNA containing an ALAS1-specific sequence is
Within the hepatocyte
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
steatosis and hepatocyte
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