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management myelodysplastic syndrome algorithm anemia aplastic cardiomyopathy differentiation dili druginduced essential et hemophilia injury liver myelodysplasia peripartum syndromes thrombocythemia
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... only curative treatment ... Myelodysplastic #Syndrome #MDS ... #treatment #hematology ... #oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... Prednisone 5mg/kg ... Renal Failure Treatment ... Differentiation #Syndrome #APML ... #hematology #oncology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
DILI) - Stepwise Diagnosis ... treatments Search ... for alternative causes ... Liver #Injury #Diagnosis ... #Algorithm #hepatology
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
normal in mild cases ... hemophilia type (e.g ... Avoid meds that ... #Management #treatment ... #hematology
Essential Thrombocythemia (ET) ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
Most cases are related ... PV, MDS, CML) Treatment ... or AML ... Thrombocythemia #ET #hematology ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... Hypocellular/Hypoplastic MDS ... aplastic anemia Treatment ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
factor (GCSF) treatments ... marrow studies Treatment ... Immunosuppressive treatment ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Peripartum Cardiomyopathy - Summary 1. Definition • Towards the end of pregnancy to 5 months postpartum
exclude other causes ... Differential Diagnosis ... with Cardio-OB team ... #management #cardiology ... #treatment
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