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management mds myelodysplastic algorithm anemia causes chronic differential lymphocytic myelodysplasia syndromes thrombocytopenia treatment workup
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
APML, CLL Acute ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Hematology #Oncology ... #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Diagnosis: • ... aplasia • ITP ... • Richter’s Syndrome ... #diagnosis #workup ... #oncology #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
dys- (abnormal) -plastic ... transformation to acute leukemia ... Allogeneic stem cell ... Management #treatment #hematology ... #oncology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Megakaryopoiesis • Aplastic ... Leukemia, Tumour ... ITP • SLE • CLL ... Non-lmmune: • HELLP Syndrome ... Algorithm #Causes #Hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... virus (EBV) • Leukemia ... #Anemia #oncology ... #hematology #diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Causes • Anemia • Aplastic ... Chronic Myelogenous Leukemia ... Cell Leukemia ... #diagnosis #hematology ... #oncology
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