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diagnosis syndrome hemophagocytic lymphohistiocytosis activation behcet capillary clarksons classification clinical finger flexor hemeonc hodgkins leak lymphoma macrophage mas msk oncology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Autoimmune diseases ... Nicolas Taar ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary ... #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Lymphohistiocytosis (HLH ... age, however the disease ... • Bicytopenia Treatment ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lymphohistiocytosis (HLH ... hypersensitivity syndromes • HLH ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Treatment Primary HLH: - HLH-94 Protocol • Dexamethasone
) Treatment Primary ... or autoimmune disease ... for refractory disease ... #Treatment #management ... #hematology
Susac Syndrome - Clinical Triad - Central nervous system dysfunction - Branch retinal artery occlusion -
- Recurrent disease ... flares - 2-year ... arterioles - Treatment ... Triad #Diagnosis #Management ... #Rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
common in Asia • HLA-B51 ... Giant retinal tears ... Arthritis, AS Treatment ... Syndrome #diagnosis #management ... signs #symptoms #rheumatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin's lymphoma (HL ... number of sites of disease ... Hodgkin Lymphoma Treatment ... classification #hematology ... #oncology #management
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... search for and treatment ... ▪ Autoimmune diseases ... Treatment Approach ... #Hematology #HemeOnc
Clarkson’s Disease - Capillary leak syndrome Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
Clarkson’s Disease ... - To treat disease ... month at least 1 year ... syndrome #diagnosis #management ... #rheumatology
Polymyalgia Rheumatica (PMR) Diagnosis and Management Summary WHAT? • Polymyalgia rheumatica (PMR) is a common systemic inflammatory
Diagnosis and Management ... bursitis, and tenosynovitis ... TREATMENT: • The ... mainstay of treatment ... #Rheumatology
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