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Pathologic Red Blood Cell (RBC) Morphologies and Associated Diseases

Acanthocyte (spur cell),  
Basophilic stippling, 
Bite cell,
Spherocyte, Teardrop ... #RedBloodCell #Morphology ... #Dyspmorphic #BloodSmear
Dacrocytes (tear drop cells) 
Other poikilocytes resemble a pear or teardrop. The narrow, tapered end
may be
resemble a pear or teardrop ... Clinical #Path #BloodSmear ... Smear #Dacrocytes #Teardrop
A – cabot ring, B – Howell-Jolly Body

What are Cabot’s rings?
- They are delicate threadlike inclusions
Pathology #Microscopy #BloodSmear ... #CabotRings
Schistocytes can assume a shape resembling natural or man-made objects such as arrowheads, fish, collar buttons,
left photo are a teardrop ... Clinical #Path #BloodSmear
Morphologic Findings in Red Blood Cells
Basophilic stippling - Small blue dots in red cells, due to
Morphologic Findings ... fragmentation Dacrocytes (teardrop ... cells) - Teardrop ... RedBloodCells #RBCs #Morphology ... #Morphologic #Diagnosis
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Blood Cell (RBC) Morphology ... Hemoglobinopathies • Teardrop ... coagulopathy (DIC) #RBC #Morphology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Blood Cell (RBC) Morphology ... S-beta thalassemia Teardrop ... BloodCell #RBC #Morphology
Several artifacts can cause significant and potentially misleading alterations to measured RBC parameters: 
1. Old samples
Poikilocytosis #CabotRings ... #Dacrocytes, #Teardrops