17 results
Primary Bone Tumors - Differential Diagnosis Algorithm 

Metastatic - Most common tumour in adults
 - Breast
Primary Bone Tumors ... • Aneurysmal Bone ... Histiocytoma #Primary #Bone ... #Bony #Tumors # ... #Causes #Oncology
Hypercalcemia - Differential Diagnosis Algorithm
Elevated PTH (High or normal):
 • Primary Hyperparathyroidism
 • Familial Hypocalciuric Hypercalcemia
Low
Granulomatous Disease ... , Lymphoma (Hodgkin ... Miscellaneous - Bone ... Hyperthyroid, Bony ... #Algorithm #causes
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
lymph node biopsy (diagnostic ... anymore • Routine bone ... number of sites of disease ... #lymphoma #diagnosis ... classification #hematology #oncology
Chronic Joint Pain - Differential Diagnosis Algorithm 
Intra-Articular
 - Bone
     • Stress
Intra-Articular - Bone ... Osgood-Schlatter Disease ... Ganglion Cyst - Bone ... #Algorithm #Orthopedics ... #Causes
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
g/dl LLN B - Bony ... more: • Clonal bone ... Causes of false- ... Gammopathies #MGUS #diagnosis ... #hematology #oncology
Pathologic / Fragility Fractures - Differential Diagnosis Algorithm 
Tumours
 - See Bone Lesions Scheme
Paget's Disease
 -
- Differential Diagnosis ... Tumours - See Bone ... • Bone Marrow ... #Algorithm #Orthopedics ... #Causes
Mastoiditis: Pathogenesis and clinical findings

Acute or Chronic Otitis Media -> 
Stage 1: Hyperemeia of the mastoid
3: Necrosis of bone ... destroying thin bony ... of the temporal bone ... or infection of bony ... inner cortical bone
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... in Sickle Cell Disease ... predispose to other orthopedic ... BrighamChiefs #Bone ... #differential #diagnosis
Vascular Joint Pain - Differential Diagnosis Algorithm 
 - Constant Pain (Ischemia)
 - Acute Onset
 -
Peripheral Vascular Disease ... fractured long bone ... • Dislocated Bone ... #Algorithm #Orthopedics ... #Causes
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
, Biological + Bone ... /ml, ↑ LDH • Bone ... Hemopathies+++: Hodgkin ... • Autoimmune diseases ... Drugs, Unknown cause