18 results
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
clinical findings • Acromegaly ... share the same pathophysiology ... rare causes of acromegaly ... overgrowth: • Carpal ... endocrinology #pathophysiology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
paresthesias (carpal ... decade → peripheral/acral ... malignancy Pathophysiology ... Differential Diagnosis ... Endocrinology #Treatment #Pathophysiology
Causes of Proximal Muscle Weakness That May Mimic Inflammatory Myopathy
 • Central or peripheral neurologic disease
or peripheral neurologic ... Endocrinopathies - Acromegaly ... mimics #diagnosis #differential ... #causes #neurology
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
- Giantism or acromegaly ... expansion (e.g. carpal ... endocrinology #pathophysiology
Causes of Peripheral Weakness with Sensory Changes - Differential Diagnosis Algorithm
Radiculopathy:
 • Disc
 • Spondylosis
 •
Sensory Changes - Differential ... Compression: • Carpal ... Weakness #Sensory #Neurology ... #Differential #
Pathophysiology Based Approach to Hyponatremia - Diagnostic Algorithm

Not the "classic" Volume based approach. 

#Hyponatremia #Algorithm #Pathophysiology
Pathophysiology ... Hyponatremia #Algorithm #Pathophysiology ... #Diagnosis #Differential ... #Nephrology #UOsm
Workup for Hyperphosphatemia - Differential Diagnosis Framework
Rule out spurious hyperphosphatemia: paraproteinemia, hyperlipidemia, hemolysis, hyperbilirubinemia, liposomal amphotericin
Hyperphosphatemia - Differential ... Hypoparathyroidism, Acromegaly ... Hyperphosphatemia #Differential ... Workup #phosphate #nephrology
Diagnostic Algorithm for Dizziness and Vertigo
Peripheral Vertigo:
 • Attacks: Sudden, severe, can last anywhere from seconds
Varies • No neurologic ... position change • Neurologic ... in semicircular canal ... Vertigo #Algorithm #differential ... #diagnosis #neurology
Hearing Loss - Differential Diagnosis Framework

Hearing Loss Types:
• Conductive
• Sensorineural
• Mixed
Presbycusis is the most common type
Hearing Loss - Differential ... include a: • Neurologic ... of the external canal ... tympanic membrane • Neurologic ... Hearing #Loss #Differential
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Hypertension - Workup and Differential ... heart failure, neurologic ... Cushing's syndrome, Acromegaly ... Neurologic disorders ... Workup #causes #Differential