10 results
Role of Uric Acid in the Inflammation of Gout

Allopurinol, Febuxostat - Xanthine oxidase
Colchicine - Release of
Inflammation of Gout ... inflammation #gout ... #uricacid #pathophysiology ... #pharmacology #
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
, Diaphoresis, Constipation ... SerotoninNorepinephrine #Inhibitors #Pathophysiology ... #Pharmacology #
Pathogenesis of Select Causes of Constipation in Adults and in Elderly

 • Mechanical (ex. Bowel Obstruction,
Select Causes of Constipation ... fibrosis of the gut ... pressure of anal canal ... transit time #constipation ... #pathophysiology
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
blurred vision constipation ... #SideEffects #Pathophysiology ... #Psychiatry #Pharmacology
Uric Acid Homeostasis
In the liver, purines are metabolized to uric acid. The last step in purine
The gout drug pegloticase ... #Homeostasis #Gout ... #Pathophysiology ... #Pharmacology #
Management of Abdominal Distension and Bloating - Treatment Algorithm

Definitions
Pathophysiology
Organic/Pathologic Etiologies:
 • Small Intestinal Bowel Overgrowth (SIBO)
Definitions Pathophysiology ... Disorders of Gut-Brain ... Chronic Idiopathic Constipation
First Generation Anti-Psychotics: Mechanisms and Side Effects
Typical/Conventional Anti-Psychotics - Examples: Haloperidol, Chlorpromazine

ACh M1 antagonist - Block
throughout body (mouth, gut ... Dry Mouth • Constipation ... #SideEffects #pharmacology
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Antiarrhythmics Pharmacology ... influx to balance out ... efflux increases out ... Antiarrhythmics #Pharmacology ... Classification #Classes #pathophysiology
Morphine Side Effects Mnemonic
MYOSIS 
OUT OF IT (SEDATION) 
RESPIRATORY DEPRESSION 
PNEUMONIA (ASPIRATION) 
HYPOTENSION 
INFREQUENCY (CONSTIPATION, URINARY
Mnemonic MYOSIS OUT ... INFREQUENCY (CONSTIPATION ... SideEffects #Adverse #Pharmacology
Allopurinol Pharmacology Summary

Xanthine oxidase inhibitor blocking the formation of new uric acid
Initiate 1-2 days prior to
Allopurinol Pharmacology ... #Allopurinol #Pharmacology ... #pathophysiology ... #gout #uricacid