29 results
diagnosis differential endocrinology management signs symptoms msk ophthalmology algorithm complications orthopedics treatment clinical growthhormone neurology pediatrics physicalexam pituitary retinopathy syndrome
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... /Symptoms: • GH ... deficiency: - Short ... expansion (e.g. carpal ... endocrinology #pathophysiology
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... GH excess prior ... • Other rare causes ... overgrowth: • Carpal ... endocrinology #pathophysiology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
paresthesias (carpal ... decade → peripheral/acral ... malignancy Pathophysiology ... or refractory cases ... Endocrinology #Treatment #Pathophysiology
Scapholunate Dissociation The spacing between all carpal bones should be 1-2 mm, look for the "Terry Thomas"
spacing between all carpal ... spacing between all carpal ... #Dissociation #TerryThomas ... Wrist #Scaphoid #Carpal ... #Orthopedics #Sports
Childhood Immunization Schedule: Why we immunize • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
URT inflammation causes ... Tetanus Toxin -> Spores ... cause quadriplegia ... lymph -> Koplik's spots ... peds #pediatrics #pathophysiology
Short Stature - Differential Diagnosis Algorithm Normal Variant, Normal Puberty Onset (BA = CA) • Familial Short
Short Stature - ... ) • Familial Short ... Constitutional Short ... Cushing's Disease • GH ... endocrinology #causes
Causes of Hypokalemia - Differential Diagnosis Algorithm Increased Loss - Increased GI Loss - Increased Urinary
Causes of Hypokalemia ... K-ATPase which imports ... Diagnosis #Algorithm #causes ... potassium #low #pathophysiology
Diagnostic Algorithm for Dizziness and Vertigo Peripheral Vertigo: • Attacks: Sudden, severe, can last anywhere from seconds
with vascular causes ... findings BPPV • Short-lived ... positional episodes caused ... in semicircular canal ... test (posterior canal
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
For pituitary masses ... following order; GH ... Headaches • Nausea ... mnemonic #GLFTAP #pathophysiology
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings Ophthalmic Artery Hypertension Stage 1: Mild/vasoconstrictive • Acute and chronic vasospasm
hyalinization causes ... BRB breakdown causes ... -> Cotton-wool Spots ... -> Elschnig's Spots ... #Retinopathy #pathophysiology
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