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diagnosis gh growthhormone abnormal abnormalities breathing disease excess feedbackloop findings lung management overproduction patterns pituitary potts summary symptoms tb tuberculosis
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates lipolysis Signs ... deficiency: - Short ... expansion (e.g. carpal ... #FeedbackLoop #endocrinology ... #pathophysiology
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
• Other rare causes ... overgrowth: • Carpal ... Overproduction #diagnosis #signs ... #symptoms #endocrinology ... #pathophysiology
Lung Findings on Physical Exam Crackles: • Short, discontinuous, sounds mostly heard during inspiration • Caused by
Exam Crackles: • Short ... alveoli as seen in pulmonary ... Lung #Findings #Pulmonary ... #PhysicalExam # ... diagnosis #signs
Pott's Disease in Tuberculosis - Diagnosis and Management Summary Epidemiology: - Typically from TB endemic areas -
extrapulmonary cases ... Clinical Signs ... years - May have signs ... symptoms of active pulmonary ... decreased reflexes Pathophysiology
Abnormalities in Rate and Rhythm of Breathing Normal The respiratory rate is about 14—20 per min
, and stop for short ... punctuated by frequent sighs ... Occasional sighs ... Breathing #Patterns #Pulmonary ... Abnormal #Diagnosis #PhysicalExam
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