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diagnosis endocrinology gh disease excess feedbackloop findings lung management overproduction pituitary potts summary symptoms tb tuberculosis
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates lipolysis Signs ... deficiency: - Short ... expansion (e.g. carpal ... metabolic abn #GrowthHormone ... endocrinology #pathophysiology
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... • Other rare causes ... overgrowth: • Carpal ... fraction • HTN #GrowthHormone ... Overproduction #diagnosis #signs
Pott's Disease in Tuberculosis - Diagnosis and Management Summary Epidemiology: - Typically from TB endemic areas -
extrapulmonary cases ... Clinical Signs ... years - May have signs ... symptoms of active pulmonary ... decreased reflexes Pathophysiology
Lung Findings on Physical Exam Crackles: • Short, discontinuous, sounds mostly heard during inspiration • Caused by
Exam Crackles: • Short ... alveoli as seen in pulmonary ... Lung #Findings #Pulmonary ... #PhysicalExam # ... diagnosis #signs
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