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Pulmonary Renal Syndrome: Investigations and Management

#Pulmonary #Renal #Syndrome #Diagnosis #Workup #Management
Pulmonary Renal ... Syndrome: Investigations ... and Management ... #Pulmonary #Renal ... #Syndrome #Diagnosis
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework
Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis
90%:
 -
Pulmonary Renal ... - Differential Diagnosis ... Kumfer @AnnKumfer #Pulmonary ... #Renal #Syndromes ... #Differential #Diagnosis
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal ... Differential Diagnosis ... for Pulmonary Renal ... #Renal #Syndrome ... #differential #diagnosis
Extrapulmonary manifestations of COVID-19
 • Neurologic: Headaches, Dizziness, Encephalopathy, Guillain-Barré, Ageusia, Myalgia, Anosmia, Stroke
 • Renal:
manifestations of COVID ... Anosmia, Stroke • Renal ... vein thrombosis, Pulmonary ... ischemia, Acute cor pulmonale ... Extrapulmonary #Diagnosis
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Pulmonary Renal ... Syndromes - OnePager ... Renal Syndromes ... #Renal #Syndromes ... #management #treatment
Complications of Portal Hypertension
 • Hepatic Encephalopathy
 • Pulmonary: Hepatopulmonary syndrome, Portopulmonary hypertension, Hepatic hydrothorax
 •
Encephalopathy • Pulmonary ... Hepatopulmonary syndrome ... Pancytopenia • Renal ... : Hepatorenal syndrome ... Complications #hepatology #diagnosis
Pharmacological Treatment of Hepatorenal Syndrome (HRS)

Midodrine - Alpha agonist incr blood pressure incr renal perfusion pressure
of Hepatorenal Syndrome ... pressure incr renal ... #HepatoRenal #Syndrome ... #Nephrology #Management ... #Pharmacology #
Anti-IL6 Agents (Tocilizumab, Siltuximab) in COVID19

IL-6 activates T cells and macrophages, among other cell types (see
Siltuximab) in COVID19 ... Cytokine Activation Syndrome ... correlate with severe COVID ... #Pharmacology # ... Management #Medications
COVID-19 Findings on Lung ultrasound
 - Thickened pleural line
 - B lines (multifocal, discrete, or confluent)
COVID-19 Findings ... alveolar interstitial syndrome ... patients with pulmonary ... GrauSegura #COVID19 ... ultrasound #POCUS #Diagnosis
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
- Differential Diagnosis ... Algorithm Syndrome ... • Drugs • Pulmonary ... GI losses • Renal ... • Nephrotic syndrome