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differential erythematosus hematology management systemic druginduced hemolytic signs symptoms testing activation approach autoantibodies autoimmune chronic cll comparison dil disease hand
Autoimmune Hemolytic Anemia (AIHA) WARM AHA - Primary - Idiopathics - Secondary Infectious • Viral- HIV, EBV, HCV, HEV •
(AIHA) WARM ... Autoimmune • Lupus ... • Rheumatoid arthritis ... #AIHA #Diagnosis ... #Differential #Algorithm
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
: - Arthritis ... - Hemolytic anemia ... involvement 3% SLE-Related ... Lupusreference #SLE ... #differential #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
(SLE) General: ... of hip (rare), Arthritis ... ) Blood (75%): Anemia ... signs #symptoms #diagnosis ... #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms, Arthritis ... • Immunologic Workup ... • Immunologic Workup ... #table #rheumatology ... #diagnosis #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Differential Diagnosis ... Hematologic: • AIHA ... lymphopenia, low PLT • Anemia ... #Rheumatology
Arthritis of the Hand - Arthritis Patterns Osteoarthritis: • Osteoarthritis of the hand usually involves the DIP and
ulnar deviation • SLE ... • MCP + PIP + Wrist ... PsA, Sickle cell anemia ... patterns #hand #diagnosis ... #rheumatology #
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential Diagnosis ... Algorithm • Sickle ... genotypes): SS, SC, SE ... #Algorithm #workup
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... joint • Systemic lupus ... the presence of anemia ... #laboratory #workup ... #Rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
SJIA], systemic lupus ... erythematosus [SLE ... with leukopenia, anemia ... Activation #Syndrome #Diagnosis ... #Rheumatology
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
to Joint Pain - Diagnostic ... spondyloarthropathies, lupus ... Chronic = RA, SLE ... Joint #Pain #MSK #rheumatology ... #approach #workup
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