36 results
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
clinical findings • Acromegaly ... share the same pathophysiology ... rare causes of acromegaly ... signs #symptoms #endocrinology ... #pathophysiology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
malignancy Pathophysiology ... Diagnosis and Workup ... glucose suppression test ... Diagnosis #Management #Endocrinology ... #Treatment #Pathophysiology
Mixing Study
 • Clotting tests can be abnormal due to either a clotting factor deficiency, or
Study • Clotting tests ... • Clotting tests ... Study #diagnosis #hematology ... #pathophysiology ... #hematology #laboratory
Diabetes Pathophysiology and Medication Targets

The ominous octet is one concept that summarizes the different pathophysiologic pathways
Diabetes Pathophysiology ... the different pathophysiologic ... ominous octet it works ... #Diabetes #Pathophysiology ... Targets #Drug #Endocrinology
Structure and function of the Adrenal Glands

#Adrenal #Glands #Function #Hormones #Actions #Pathophysiology #Endocrinology

** GrepMed Recommended Text:
Hormones #Actions #Pathophysiology ... #Endocrinology ... GrepMed Recommended Text
Algorithm for Investigation of Abnormal Coagulation Tests
- Prolonged PT
- Prolonged aPTT and Prolonged PT
- Prolonged aPTT

Dr.
Abnormal Coagulation Tests ... APTT #Laboratory #Hematology ... #Diagnosis #Workup
Hyperthyroidism (low TSH, High T4/T3) - Diagnostic Algorithm

Radioactive iodine scan – get if concern for nodular
Check pregnancy test ... affects diagnostic workup ... Diagnosis #Algorithm #Workup ... #Endocrinology
Acromegaly Testing Algorithm
INDICATIONS FOR TESTING:
 • Adults – enlarged facial or acral features, abnormal musculoskeletal growth
Acromegaly Testing ... linear growth Tests ... Glucose Tolerance Test ... ARUPConsult @ARUPLabs #Acromegaly ... Algorithm #diagnosis #endocrinology
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
- Giantism or acromegaly ... #FeedbackLoop #endocrinology ... #pathophysiology
The principal endocrine 'axes' and glands. Parathyroid glands, adrenal zona glomerulosa and endocrine pancreas are not
abbreviations see text ... Endocrine #Axes #Endocrinology ... #Pathophysiology