5 results
Thiopurines in IBD
Indications:
 • Steroid-sparing agents indicated for maintenance of remission in UC and CD
 •
Thiopurines in IBD ... Metabolism: • Thiopurine ... activity: avoid thiopurines ... 1.5mg/kg TDM (thiopurine ... @JeanDonet #Thiopurines
Thiopurine De-escalation and IBD - Management Algorithm
IBD Patient on Thiopurine Interested in Discontinuing Thiopurine
Assess Disease Activity:
Thiopurine De-escalation ... IBD Patient on Thiopurine ... Discontinuing Thiopurine ... Indication for Thiopurine ... Waseem_AhmedMD #Thiopurine
Persistent UC Symptoms Despite 5-ASA Therapies
 • Assess for Drug Adherence
 • Disease Activity Assessment (bloody
options: - Thiopurines
Treatment Schema for Standard-Risk Acute Lymphoblastic Leukemia
Induction: 
 • Vincristine, Steroid (dexamethasone), L-Asparaginase, Intrathecal (IT) methotrexate
Consolidation
Vincristine, Steroid, Thiopurine
Fatigue and IBD Algorithm
 • 40-50% patients have fatigue despite clinical remission
 • Risk factors: BMI,
disturbance, Female, Thiopurine