15 results
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Low Alkaline Phosphatase ... collection with EDTA Pathophysiology ... mineralization Symptoms ... respiratory failure • Neurologic ... Hyophosphatasia #hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
) Pathophysiology ... postpartum): • Initial symptoms ... Liver #Pregnancy #hepatology ... obgyn #diagnosis #management ... #pathophysiology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... PBC Signs and Symptoms ... PBC Labs: • Alkaline ... obstruction • ALP ... diagnosis #workup #hepatology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
lymphocyte predominant (LP ... pattern of spread, B symptoms ... Lymphoproliferative #Disorders #Classification ... #pathophysiology ... #Hematology #Diagnosis
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
suspected HH based on symptoms ... Step 3: All patients ... including liver and hematologic ... ALT, alanine aminotransferase ... algorithm #diagnosis #management
Post-Transplantation Lymphoproliferative Disorders (PTLD)
Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
accounts for 21% of all ... regimen Signs/Symptoms ... , unexplained hematologic ... Diagnosis and classification ... oncology #diagnosis #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Incidence: common in APL ... ATRA treatment Pathophysiology ... Diagnosis: >3 symptoms ... APML #diagnosis #management ... #hematology #oncology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Lateral Sclerosis (ALS ... lateral sclerosis Pathophysiology ... fasciculations Common Symptoms ... Lateral #Sclerosis #neurology ... #diagnosis #management
Hepatic Encephalopathy - Diagnosis and Management Summary
Definition:
 • Alteration in brain function manifested by neuropsychiatric symptoms
Diagnosis and Management ... neuropsychiatric symptoms ... other causes of neurologic ... Encephalopathy #Grading #Classification ... #Diagnosis #Management
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... ingestion • B symptoms ... -95% of cases) Classification ... #hematology #oncology ... #management