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hepatology algorithm causes transaminitis aptt coagulation hepatitis injury prolonged aflp bleeding bruising chemistry cholestatic comparison disease hellp hemostasis hepatocellular icp
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
Liver Enzymes (LFTs ... more specific for hepatic ... #Enzymes #LFTs ... Transaminitis #diagnosis ... #differential #
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... - Differential ... Diagnosis Algorithm ... disease US — Normal ... • Others #LFTs
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Coagulation factors: PT ... replaced by non-hepatic ... Enzyme Elevation ... #chemistry #diagnosis ... #differential #
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... - Hemolysis, NASH ... #LFTs #transaminitis ... #differential # ... diagnosis
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
imaging: Normal ... enzymes, and Low ... Disease #Pregnancy #hepatology ... hepatitis #comparison #differential ... #diagnosis #icp
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... the magnitude of enzyme ... #LFTs #Abnormal ... #Liver #Enzymes ... #Differential #
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... • Reduced liver ... amyloidosis #Abnormal ... #differential # ... hematology #coagulation
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Diagnosis Algorithm ... Injury: • Hepatic ... Enzyme Elevation ... #hepatology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... Early liver disease ... #Causes #diagnosis ... #differential # ... hematology #coagulation
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
PT/NORMAL PTT: ... PT/ABNORMAL PTT ... PT/NORMAL PTT: ... PT/ABNORMAL PTT ... #Diagnosis #Hematology
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