9 results
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Liver Enzymes (LFTs ... for hepatic pathology ... Transaminitis #diagnosis ... #differential # ... hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs ... replaced by non-hepatic ... #chemistry #diagnosis ... #differential # ... #LFTs #RValue #
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Diagnosis Algorithm ... dz Cholestatic ... Burak @kwburak #LFTs
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... Diagnosis Algorithm ... Injury: • Hepatic ... Venoocclusive disease • Hepatic ... #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... - Differential ... Diagnosis Algorithm ... • Others • Cholestatic ... • Others #LFTs
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
) Elevation - Differential ... Diagnosis Algorithm ... Highest • Bone • Liver ... elevation DDX of Hepatic ... #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Injury - Differential ... Diagnosis Framework ... phosphatase) 2) Cholestatic ... #Diagnosis #hepatology ... Transaminitis #LFTs
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Intrahepatic Cholestasis ... Histology: Normal-mild cholestasis ... Disease #Pregnancy #hepatology ... hepatitis #comparison #differential ... #diagnosis #icp
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
→ Cirrhosis/Liver ... obstruction • ALP ... bile ducts Differential ... malignancies, Hepatic ... #workup #hepatology