15 results
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
and bridging for VTE ... Anticoagulant #Anticoagulation ... #Dabigatran #Apixaban ... #Rivaroxaban #Edoxaban ... #Pharmacology #Hematology
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
Renal Dosing: Apixaban ... 60kg, CrCl 15-50 Rivaroxaban ... OralAnticoagulant #Anticoagulation ... #Hematology #Pharmacology ... #Apixaban #Rivaroxaban
Xa Inhibitors - Apixaban and Rivaroxaban 
Oral Xa inhibitors are recommended by CHEST as first-line for
Xa Inhibitors - Apixaban ... and Rivaroxaban ... patients with VTE ... Fibrillation requiring anticoagulation ... for VTE tx and
Choice of anticoagulant for treatment of pulmonary embolism
 • Malignancy - LMWH
 • To avoid parenteral
; apixaban • Once ... oral therapy - Rivaroxaban ... Gl bleed - VKA, apixaban ... #decisionaid #vte ... #anticoagulation
Switching Between Anticoagulants and DOACs
VKA, Dabigatran, Rivaroxaban, Apixaban, Edoxaban, Betrixaban, DOAC, Parenteral anticoagulant

DOI: 10.1161/JAHA.120.017559

#Anticoagulants #DOACs #anticoagulation
VKA, Dabigatran, Rivaroxaban ... , Apixaban, Edoxaban ... Anticoagulants #DOACs #anticoagulation ... #Switching #hematology
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
(Praxbind) - Apixaban ... Edoxaban (Lixiana), Rivaroxaban ... PCC (Kcentra) #anticoagulation ... #pharmacology #hematology
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
, edoxaban and rivaroxaban ... body mass index; VTE ... #DOAC #VTE #Malignancy ... #Anticoagulation ... #Management #Hematology
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
Pathophysiology Anticoagulation ... the mainstay of VTE ... warfarin) for chronic anticoagulation ... - Rivaroxaban ... DOAC #Dabigatran #Apixaban
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
interactions) Cancer-treatment ... Edoxaban, rivaroxaban ... , and apixaban are ... Rivaroxaban and ... Chemotherapy #Oncology #Hematology
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
algorithm for VTE ... thrombosis in cancer ... #Cancer #Algorithm ... #Anticoagulation ... #Management #Hematology