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diagnosis hematology management leukemia photo syndrome causes classification hodgkins infectiousdiseases lymphocytic lymphoma myelodysplastic rheumatology skin agglutinin anemia apml basophilia basophils
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Malaise, bleeding, infections ... pain, bleeding, infections ... bruising, bleeding, infection ... violaceous, nontender cutaneous ... #Oncology #Diagnosis
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
Cutaneous manifestations ... Infectious manifestations ... myelodysplastic #syndrome #differential ... #diagnosis #dermatology ... #oncology #clinical
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
e.g., HIV), EBV infection ... Etiology: - Infections ... disease: GI, neuro, cutaneous ... NonHodgkins #comparison #oncology ... #hematology
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
Basophilia - Differential ... which are released during ... Disorders: • Chronic ... Diabetes/DKA Infections ... : • helminth infections
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
- Due to Viral infection ... Polyclonal - Viral Infection ... Clinical Presentation ... Check For: • Infections ... Polyclonal IgM post infectious
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Orange or Hep C Clinical ... weeks without infection ... diagnosis #workup #oncology ... #hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
hypogammaglobulinemia -> increased infection ... history of recurrent infections ... disease • Infectious ... community-acquired infections ... infections (Epstein-Barr
Ulcerative Blastomycosis Skin Lesion 57 asymptomatic M from Indiana nonpruritic, painless, progressive skin lesion lower back x
heaped up borders); differential ... : basal cell ca, ... squamous cell ca ... Indiana University Infectious ... #clinical #photo
Clinical Classification of Pulmonary Hypertension 1. Pulmonary arterial hypertension from pulmonary vasculopathy Idiopathic pulmonary arterial hypertension Heritable gene mutations
Clinical Classification ... diseases - HIV infection ... Chronic thromboembolic ... Langerhans cell ... Classification #Diagnosis #Differential
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... Leukemia (CLL) ... immunophenotype Clinical ... Complications: 1) Infection ... #Leukemia #oncology
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