11 results
Spectrum of activity for systemic antifungal agents
Antifungals: 5FC, flucytosine; AMB, amphotericin B; ANI, anidulafungin; CAS, caspofungin;
activity for systemic antifungal ... agents Antifungals ... .2015.10.012 #Antifungal ... #antibiogram #management ... #pharmacology #
Flutycosine - Antibiotics Class Overview
 - 
Mechanism: 5-FC interferes with DNA and protein synthesis.  Only
B for initial management ... - Virtually never ... for non-severe candida ... #Pharmacology #Antibiotics ... #Flutycosine #Antifungal
Antifungal Echinocandins  - Antibiotics Class Overview

Mechanism: Inhibit glucan synthesis in fungal cell wall by blocking
Antifungal Echinocandins ... Cidal vs Candida ... choice for severe Candida ... salvage therapy, never ... Anidulafungin #Pharmacology
IDSA Recommendations for Treating Mucosal Candidiasis in HIV-AIDS
Oropharyngeal Candidiasis: Initial Episodes (Duration of Therapy: 7–14 days)
Preferred
Note: Systemic antifungals ... #Candidiasis #candida ... Prevention #Treatment #management ... infections #HIVAIDS #pharmacology
Candida Glabrata
Species of Candida Most Commonly Isolated in Bloodstream Infections
 • Symptomatic mucosal infection is detected
with persistent fever ... unresponsiveness to antifungal ... time to azole antifungals ... candidemia #diagnosis #management ... #fungemia #management
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan
Beta-D-Glucan:
 • Polysaccharide cell wall component of many fungi
 • Pathogens:
• Pathogens: Candida ... BAL GM does not differentiate ... of mold-active antifungals ... post-2010 almost never
Liver Abscess and Mimics - Differential Diagnosis
Most Common: Polymicrobial, E Coli, Klebsiella, Strep/Enterococcus, Staph, Anaerobes
Infectious Differential:
Liver Abscess and ... Mimics - Differential ... bartonella - Fungal: Candida ... #Abscess #Differential ... Diagnosis #hepatology #management
Myasthenic Crisis Checklist - Myasthenia Gravis

Evaluation 
 - Chest X-ray and lung ultrasound (exclude other lung
Phos), CBC with differential ... workup or TSH level ... ://twitter.com/PulmCrit ... MyastheniaGravis #Checklist #Management
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Parvovirus B19 • Candida ... Leishmaniasis Differential ... -6 weeks after antifungal ... Inflammatory #Syndrome #Differential ... #Diagnosis #Management
Overview of antifungal agents benefits, weaknesses, and adverse effects in the treatment of Coccidioidomycosis.
Fluconazole - Low
Overview of antifungal ... hypokalemia, phlebitis, fever ... #valleyfever #management ... #treatment #antifungals ... comparison #table #pharmacology