11 results
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... syndromes Clinical ... is the main clinical ... #Diagnosis #Management ... #Hematology #Rheumatology
ED Opioid Stewardship Algorithm

Opioid Naive vs Opioid Tolerant

1. Patient Specific, Pain Syndrome-Targeted Approach
2. Combinations of Non-Pharmacologic
Opioid Stewardship Algorithm ... Patient Specific, Pain ... Syndrome-Targeted ... Combinations of Non-Pharmacologic ... #Management #Pain
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Differential Diagnosis Algorithm ... Renal Failure • Liver ... Neoplastic / Hematologic ... Myasthenia Gravis Pharmacologic ... Chronic Fatigue Syndrome
Flutycosine - Antibiotics Class Overview
 - 
Mechanism: 5-FC interferes with DNA and protein synthesis.  Only
B for initial management ... - Virtually never ... infections) - Main ... adverse effects = Hematologic ... #Pharmacology #Antibiotics
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... following: • Fever ... agent are the main ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Pain, Agitation, and Delirium (PAD) in the ICU
Addressing the ICU Triad (PAD) can be accomplished through
tool to assess level ... Propofol infusion syndrome ... No pharmacologic ... (Haldol) - No pharmacologic ... CriticalCare #diagnosis #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... effusions, weight gain ... Differentiation #Syndrome ... APML #diagnosis #management ... #hematology #oncology
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
Diagnosis and Management ... sex • Metabolic syndrome ... swelling, significant pain ... Gout #diagnosis #management ... #treatment #rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... vasculitis: 10%-16% Liver ... Nephrogenic DI Hematologic ... lubricants • Pharmacologic ... Diagnosis #Management
Relapsing Polychondritis

What is it?
Recurrent inflammation of the cartilage in the body (Autoimmune disorder)

Who?
• Most frequently: 40
Sudden onset of pain ... Nonspecific symptoms: Fever ... • MAGIC syndrome ... Polychondritis #rheumatology ... #diagnosis #management