32 results
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
is the main clinical ... ALT ↑ bilirubin level ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome ... Behcets #disease #Syndrome ... #Treatment #management ... #pharmacology # ... rheumatology
Adjuvant therapies in critical care: steroids to treat infectious diseases
 - Severe Community Acquired Pneumonia
Pneumonia - Typhoid fever ... respiratory distress syndrome ... InfectiousDiseases #Infections #Pharmacology ... #Management #Treatment
ED Opioid Stewardship Algorithm

Opioid Naive vs Opioid Tolerant

1. Patient Specific, Pain Syndrome-Targeted Approach
2. Combinations of Non-Pharmacologic
Syndrome-Targeted ... Combinations of Non-Pharmacologic ... Medication Assisted Treatment ... Stewardship #Algorithm #Management ... #Pain #ED
Orthopedic Emergencies
Compartment Syndrome
 • An increase in compartment pressure to the point where tissue perfusion is
Ensure leg is at level ... - Intense pain ... days, the local pain ... including DM • Treatment ... #treatment
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... • Bicytopenia Treatment ... agent are the main ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- 80% have fever ... organ damage • Treatment ... Low calcium • Treatment ... TLS #diagnosis #management ... #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... effusions, weight gain ... APML #diagnosis #management ... #hematology #oncology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Framework and Management ... symptoms: - Muscle pain ... Muscle swelling - Fever ... - Abdominal pain ... Differential #Diagnosis #Management
Renal Cell Carcinoma (RCC) - Diagnosis and Management Summary
Clinical features - Classic triad (flank pain, hematuria,
Diagnosis and Management ... night sweats, fever ... Budd Chiari syndrome ... disease Imaging and Treatment ... RCC #Diagnosis #Management