17 results
Leser–Trélat Sign on Physical Exam

Acute onset of multiple seborrheic keratoses, often a paraneoplastic sign of malignancy.

#Leser
Leser–Trélat Sign ... paraneoplastic sign ... #Leser #Trélat # ... #LeserTrelat #Sign ... #video #skin #dermatology
Erythematous Rashes - THE ALGORITHMIC APPROACH

Characterized by diffuse redness of the skin due to
capillary congestion, erythematous
or absence of fever ... the Nikolsky sign ... the Nikolsky sign ... or Nikolsky sign ... #Diagnosis #Dermatology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Illness Script Signs ... if neutropenic fever ... Anemia #diagnosis #management ... #treatment #hematology
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
red-flags to exclude dermatologic ... Ill-appearing, vital sign ... instability - New-onset fever ... #Diagnosis #Dermatology
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
chest (in a V-sign ... shoulders (in a shawl sign ... Inverse Gottron’s sign ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
Combination of Skin Findings and Arthritis in Pediatrics Patient - Differential Diagnosis
Malar rash: 
 • A
not be seen try focus ... Suggestive of: Rheum Fever ... migrans: • Target sign ... gabrieltalledop #dermatology
Bullous Pemphigoid - Diagnosis and Management Summary
Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Diagnosis and Management ... dermis Clinical Signs ... erosions in ~20% Management ... Pemphigoid #Diagnosis #Management ... #dermatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Diagnosis: HLH signs ... following: • Fever ... lymph node, or liver ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Post-Transplantation Lymphoproliferative Disorders (PTLD)
Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
in lung>heart>liver ... Conditioning regimen Signs ... symptoms, unexplained hematologic ... EBV viral load, signs ... oncology #diagnosis #management
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- 80% have fever ... WBC >100k, + lab signs ... TLS #diagnosis #management ... #hematology