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Tigecycline (IV) - Antibiotics Class Overview

Mechanism: Glycylcycline class - structurally related to Tetracyclines (bacteriostatic).  Only
Tigecycline (IV) ... Review #Overview #Tigecycline
Antibiotics with MRSA Coverage

Oral: Doxycycline, Minocycline, Clindamycin, TMP-SMX
IV: Vancomycin, Daptomycin, Telavancin, Ceftaroline, Dalbavancin, Oritavancin, Tigecycline
Oral and
, Oritavancin, Tigecycline
Antibiotic Options for Treating MRSA Infections

PO: Doxycycline, Clindamycin, TMP-SMX, Linezolid
IV: Linezolid, Vancomycin, Ceftaroline, Daptomycin, Tigecycline

By Dr.
Ceftaroline, Daptomycin, Tigecycline
Antibiotics - Mechanisms and Sites of Action 

Inhibit Cell Wall Synthesis or Function 
- Beta Lactams,
Tetracyclines, Tigecycline
Antibiotics and CNS Diffusion

1. Drugs with good CNS diffusion:

- Fluoroquinolones, Fluconazole, voriconazole, Rifampin, Oxazolidinones, Metronidazole

2. Drugs
Daptomycin, Colimycin, Tigecyclin
General Bacterial Antibiogram - Antibiotics and Spectrum of Coverage
Make sure you consult your local antibiogram!
VRE -
doxycycline) - tigecycline
Carbapenem Resistant Organisms - Antibiogram
KPC-producer, NDM-producer, OXA-48-like-producer, Carbapenem-resistant Pseudomonas aeruginosa, Carbapenem-resistant Acinetobacter baumannii, Stenotrophomonas maltophilia
 •
or Colistin • Tigecycline
Bacteremia Quick Reference - Treatment Duration

Gram Negative Bacteremia:
 • Avoid: Aminoglycosides and tigecycline
 • Catheters should
Aminoglycosides and tigecycline
Intern Pocket Cards - Antibiogram and Susceptibilities
VRE - MRSA - GRAM POSITIVES - GRAM NEGATIVES -
doxycycline) - tigecycline
ANTIBIOTICS WITH ANAEROBE COVERAGE - Antibiotics Class Overview
 1. Metronidazole (Flagyl)(PO and IV)
 2. Clindamycin –
Tigecycline – excellent