11 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Joint Pain Rash ... gangrenosum • IBD ... Antiphospholipid-antibody syndrome ... #rashes #differential ... #diagnosis #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... Demyelinating syndromes ... erythematosus #signs
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... Clinical Presentation ... Petechial or purpuric rash ... erythematosus [SLE ... #Rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... 3rd Decade Skin ... permanent alopecia Differential ... Clinical Features ... Chronic B-cell activation
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
(Clinical Dx). ... Behcet disease) Differential ... Oral aphthae : SLE ... diagnosis #management #signs ... #symptoms #rheumatology
Henoch Schonlein Leg Rash - Palpable Purpura
Purpura: Low Platelets or Vasculitis?
45 years old, seen in our
45 years old, seen ... Tip: To differentiate ... later confirmed by skin ... #clinical #photo ... #dermatology #HSP
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitides - Differential ... mucositis - Rash ... purpura: strong sign ... vasculitis, and SLE ... #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
diseases, such as SLE ... purpura: Strong sign ... of shoulder and hip ... , mucositis • Rash ... #Diagnosis #Rheumatology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... Agent Orange or Hep ... C Clinical Presentation ... Physical Exam/Signs ... Hepatomegaly • Skin
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
• Excessive activation ... Transverse Myelitis - Clinical ... • Bilateral signs ... Disorders: - SLE ... management #neurology #differential