11 results
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... mucositis - Rash ... aphthous ulcers, cutaneous ... purpura: strong sign ... of cutaneous leukocytoclastic
Tinea Capitis in a Newborn- A 3-week-old male newborn was brought to the pediatrician with three
Newborn- A 3-week-old ... Somalia, had similar skin ... ringworm, was diagnosed ... #clinical #photo ... #ringworm #derm
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - Diagnostic ... : - Catch-all term ... , vital sign instability ... sulfa-drug - Skin ... #Dermatology #Rash
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
response -> Subacute cutaneous ... inflammation on skin ... Livedo Reticularis, Vasculitis ... pathophysiology #diagnosis ... #signs #symptoms
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
DERMATOMYOSITIS Cutaneous ... (blue-purple) rash ... • Erythematous rash ... chest (in a V-sign ... #dermatology #diagnosis
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Diagnosis Framework ... Differential Diagnosis ... purpura: Strong sign ... of cutaneous leukocytoclastic ... , mucositis • Rash
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
Interleukin 8 (IL8 ... histopathologic term ... response) - Cutaneous ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
sudden onset of a rash ... - Rash: multiple ... Most common extra cutaneous ... Episcleritis Signs ... Leukocytoclastic vasculitis
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
in the neck Cutaneous ... (blue-purple) rash ... • Erythematous rash ... chest (in a V-sign ... Dermatomyositis: • ILD
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... Differential Diagnosis ... CNS • Headache, mild ... Seizures • Strokes Skin ... Erythematosus #Diagnosis