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differential rheumatology dermatology syndrome clinical lupus systemic vasculitis activation antimda5 antimda5dm autoimmune capillaritis classification compared comparison dermatitis dermatomyositis dermatoses dermatosis
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Associated with Joint Pain ... Rash • Human ... • Rheumatic fever ... lesions • Discoid ... differential #diagnosis
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
) General: Fever ... Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... Abdominal pain ... (20%) Renal disease
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... 3rd Decade Skin ... rash • Erythematous ... papulosquamous lesions ... Arthritis: • Joint pain
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Sweet Syndrome Acute ... with systemic disease ... sudden onset of a rash ... - Rash: multiple ... Inflammation and pain
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
rash on the face ... lesions: antihelix ... Dermatomyositis • Fever ... severity of the disease ... #dermatology #diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
lesions • Mononeuritis ... : erythematous nodules ... mucositis - Rash ... Vasculitis: • Fevers ... vasculitis, and SLE
Erythemas Summarized Erythema ab igne • A dermatosis that results from repeated exposure to heat (fires, heating
centrifugum • A chronic skin ... presenting with erythematous ... observed in acute ... classic targetoid lesions ... #differential #diagnosis
Leg Pain - Differential Diagnosis Framework Bone/Joint Causes of Leg Pain: • Fracture • Arthritis • Gout/pseudogout
Diagnosis Framework ... • Bursitis • IBD ... Immobilization) • Acute ... /swelling - Fever ... extremity #msk #physicalexam
Pustular Skin Lesions - Differential Diagnosis Framework What are pustules? • Pustules < 5-10 mm + pus • Material
Pustular Skin Lesions ... Generalized itchy rash ... with rheumatic pain ... Pustules + Fever ... Acute generalized
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Systemic lupus erythematosus ... is the main clinical ... Petechial or purpuric rash ... [SLE], AOSD) • ... Activation #Syndrome #Diagnosis
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