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rheumatology dermatology differential clinical sle syndrome systemic vasculitis activation algorithm antimda5 antimda5dm autoimmune causes classification dermatitis dermatomyositis erythema extremity foot
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Associated with Joint Pain ... Rash • Human ... • Rheumatic fever ... lesions • Discoid lupus ... differential #diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... 3rd Decade Skin ... Differential Diagnosis ... Arthritis: • Joint pain ... to: Arthritis, Fever
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
(SLE) General: Fever ... Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... lesions Abdominal pain ... (20%) Renal disease
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Systemic lupus ... erythematosus ... Petechial or purpuric rash ... erythematosus [ ... Activation #Syndrome #Diagnosis
Moccasin-variety Tinea Pedis 70 M chronic scaly feet. Over the years: rash has itched only occasionally;
Over the years: rash ... Diagnosis? ... sp. pruritic, erythematous ... skin of inflamed ... type #clinical #photo
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
: erythematous nodules ... mucositis - Rash ... such as systemic lupus ... erythematosus, ... Vasculitis: • Fevers
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
with systemic disease ... sudden onset of a rash ... - Rash: multiple ... Inflammation and pain ... ’s syndrome - Lupus
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Red Flags: • Fever ... lesions • Severe pain ... Autoimmune Vasculitis (lupus ... cryoglobulins • Skin ... #dermatology #physicalexam
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
(blue-purple) rash ... rash on the face ... Dermatomyositis • Fever ... severity of the disease ... #dermatology #diagnosis
Leg Pain - Differential Diagnosis Framework Bone/Joint Causes of Leg Pain: • Fracture • Arthritis • Gout/pseudogout
Diagnosis Framework ... Legg-Calve-Perthes disease ... • Bursitis • IBD ... /swelling - Fever ... extremity #msk #physicalexam
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