13 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Rash • Human ... • Rheumatic fever ... Antiphospholipid-antibody syndrome ... lesions • Discoid lupus ... differential #diagnosis
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
(SLE) General: Fever ... Sjögrens (15%) Skin ... Demyelinating syndromes ... lesions Abdominal pain ... (20%) Renal disease
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
with systemic disease ... sudden onset of a rash ... - Rash: multiple ... Inflammation and pain ... - Lupus - Leukemia
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
• Systemic lupus ... is the main clinical ... Petechial or purpuric rash ... Fibrin degradation products ... #Diagnosis #Management
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... 3rd Decade Skin ... Differential Diagnosis ... Arthritis: • Joint pain ... to: Arthritis, Fever
The Stages of Syphilis 

Primary Syphilis 
- The chancre lesion is the hallmark of primary syphilis.
- Rash, pink ... of pain and sensory ... granuIomas on skin ... Latent #Tertiary #Diagnosis ... of Infectious Diseases
Syphilis - Clinical Manifestations and Treatment

1) Primary Syphilis
 • Direct lesion contact during sex is responsible
→ Ulcerates to produce ... Presentation: Fever ... weight loss • Skin ... : Rash is the most ... #stages #diagnosis
Pustular Skin Lesions - Differential Diagnosis Framework

What are pustules?
• Pustules < 5-10 mm + pus
• Material
- Differential Diagnosis ... Generalized itchy rash ... with rheumatic pain ... Pustules + Fever ... Secondary syphilis
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
inflammation Others: • Lupus ... Coronary arteries - Fever ... mucositis - Rash ... such as systemic lupus ... Vasculitis: • Fevers
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
• Domestic and wild ... Milk • Food products ... Lady Windermere Syndrome ... : • Syndrome of ... diarrhea, abdominal pain