56 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... triad: Fever, Arthralgia ... /arthritis, Skin ... rash ± odynophagia ... #Disease #diagnosis
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Rash • Human ... infection Malar rash ... • Rheumatic fever ... gangrenosum • IBD ... differential #diagnosis
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... Disease Systemic ... with urticarial rash ... maculopapular skin ... #Adult #onset #Stills
Erythematous Rashes - THE ALGORITHMIC APPROACH

Characterized by diffuse redness of the skin due to
capillary congestion, erythematous
redness of the skin ... staphylococcal scalded skin ... includes Kawasaki disease ... erythematous rash ... #Erythematous #Rash
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's ... Disease (AOSD) ... : High spiking fever ... maculopapular rash ... #Disease #AOSD
Fever Patterns - Differential Diagnosis Framework

Continuous Fever:
Temp > 38°C with only 1 degree fluctuation in 24
Differential Diagnosis ... : • Still's disease ... • Hyper-IgD syndrome ... Brucellosis Faget's Sign ... #Differential #Diagnosis
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - Diagnostic ... , vital sign instability ... - New-onset fever ... sulfa-drug - Skin ... pain - Immunocompromised
Biphasic Illness of Leptospirosis
Some patients do not progress to severe disease. Others, rapidly develop severe disease
-14 days): • Fever ... maculopapular rash ... vomiting, abdominal pain ... Biphasic #Phases #Diagnosis ... #Illness #Signs
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
Skin rash and malaise ... The signs and symptoms ... ) ▪ Malaise, fever ... #Diagnosis #Clinical ... #Photo #Dermatology
Acute Purpura Fulminans Skin Rash on Physical Exam 
60 year old male ITP s/p splenectomy 
1d
Purpura Fulminans Skin ... Exam 60 year old ... splenectomy 1d chills ... BIDMC Infectious Diseases ... #photo