14 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Joint Pain Rash ... • Rheumatic fever ... Antiphospholipid-antibody syndrome ... lesions • Discoid lupus ... #differential #diagnosis
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - Diagnostic ... instability - New-onset fever ... with rash - Mucocutaneous ... sulfa-drug - Skin ... #Dermatology #Rash
ID Approach to Fever and Rash - Diagnostic Algorithm
Central Maculopapular (most common):
Measles, Parvovirus 819 / EBV,
ID Approach to Fever ... and Rash - Diagnostic ... angiomatosis, Sweet syndrome ... #Rash #Febrile ... #Schema #InfectiousDiseases
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
sudden onset of a rash ... - Rash: multiple ... general feeling of ill ... - Lupus - Leukemia ... cutis Diagnosis
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
(SLE) General: Fever ... Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... Demyelinating syndromes ... signs #symptoms #diagnosis
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... 3rd Decade Skin ... Differential Diagnosis ... Seizures • Strokes Skin ... to: Arthritis, Fever
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
disease • Systemic lupus ... - Nonremitting fever ... Petechial or purpuric rash ... SJIA], systemic lupus ... #Diagnosis #Management
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
rash in association ... Fever >38.5 2. ... Skin involvement ... withdrawal • Mild ... SinaiBmoreIMRes #DRESS #Syndrome
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
inflammation Others: • Lupus ... Coronary arteries - Fever ... mucositis - Rash ... such as systemic lupus ... Vasculitis: • Fevers
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... survival is 93-95% Pathophysiology ... General: fever, ... nodes: 13-15%, skin ... (16-32%): lupus