15 results
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's ... : High spiking fever ... maculopapular rash ... : high fever, CRP ... #management #treatment
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... maculopapular skin ... mL Gf consider MAS ... Stills #disease #AOSD ... #management
Erythematous Rashes - THE ALGORITHMIC APPROACH

Characterized by diffuse redness of the skin due to
capillary congestion, erythematous
redness of the skin ... usually to TEN in adults ... syndrome (SSS) ... erythematous rash ... Nikolsky sign may
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - Diagnostic ... instability - New-onset fever ... with rash - Mucocutaneous ... sulfa-drug - Skin ... #Dermatology #Rash
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
(MAS) Classified ... arthritis (sJIA) • Adult-onset ... Petechial or purpuric rash ... erythematosus [SLE], AOSD ... #Diagnosis #Management
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Clinical triad: Fever ... Arthralgia/arthritis, Skin ... rash ± odynophagia ... Complications: MAS
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
sudden onset of a rash ... - Rash: multiple ... general feeling of ill ... Leukemia cutis Diagnosis ... #diagnosis #dermatology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
rash in association ... eruption that may ... Fever >38.5 2. ... withdrawal • Mild ... SinaiBmoreIMRes #DRESS #Syndrome
Chronic Abdominal Pain Causes - Differential Diagnosis Framework

Many patients with chronic abdominal pain have had prior
- Differential Diagnosis ... Red Flags: • Fever ... • Abdominal mass ... Back pain • Skin ... appendages • FMF • Adult
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... 3rd Decade Skin ... Differential Diagnosis ... rheumatoid arthritis, adult-onset ... to: Arthritis, Fever