17 results
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... maculopapular skin ... Treatment - Mild ... #Adult #onset ... #rheumatology #management
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Clinical triad: Fever ... Arthralgia/arthritis, Skin ... rash ± odynophagia ... #management #treatment
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's ... : High spiking fever ... maculopapular rash ... Systemic AOSD: high fever ... #management #treatment
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
sudden onset of a rash ... - Rash: multiple ... general feeling of ill ... Treatment: - Systemic ... #diagnosis #dermatology
Fever vs Hyperthermia
Fever:
 • Regulated in the hypothalamic thermoregulatory center
 • "Set point" raised by prostaglandin
Neuroleptic malignant syndrome ... ; Serotonin syndrome ... loss from the skin ... Hyperthermia #comparison #diagnosis ... #management #treatment
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
rash in association ... Fever >38.5 2. ... withdrawal • Mild ... disease: symptomatic treatment ... SinaiBmoreIMRes #DRESS #Syndrome
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
arthritis (sJIA) • Adult-onset ... - Nonremitting fever ... Petechial or purpuric rash ... Treatment: • Corticosteroids ... #Diagnosis #Management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... cytokines (TNFa,lL1, IL6 ... • Clinical: fever ... diseases: SLE+++, Adult-onset ... #management #treatment
Orthopedic Emergencies
Compartment Syndrome
 • An increase in compartment pressure to the point where tissue perfusion is
fractures in young adults ... • Diagnosis: ... over the involved skin ... - Fever, ... #management #treatment
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
Deficiency) - Diagnosis ... and Management ... integrity of: • Skin ... vasculitis Treatment ... #Management