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management dermatology differential disease stills aosd blood hematology product reactions treatment adult algorithm antimda5 antimda5dm autoimmune color criteria ddxof dermatomyositis
Adult Onset Still's Disease - Yamaguchi Criteria Major criteria: - Fever >= 39C lasting >= 1 weeks
weeks - Typical skin ... rash: maculopapular ... polyarteritis nodosa #AdultOnset ... Yamaguchi #Criteria #Diagnosis ... #Major #Minor #Rheumatology
Maculopapular - Diagnostic Algorithm Pathophysiology: - Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - ... Diagnostic Algorithm ... instability - New-onset fever ... sulfa-drug - Skin ... #Maculopapular
Adult-Onset Still's Disease (AOSD) Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
: High spiking fever ... salmon-colored maculopapular ... rash, arthritis ... BrighamChiefs #AdultOnset ... Disease #AOSD #rheumatology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad: Fever ... Arthralgia/arthritis, Skin ... rash ± odynophagia ... Prunelle Getten #AdultOnset ... management #treatment #rheumatology
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
with urticarial rash ... Rash: • Nonpruritic ... nonpruritic macular or maculopapular ... skin rash that ... #rheumatology #
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Joint Pain Rash ... • Rheumatic fever ... gangrenosum • IBD ... #differential #diagnosis ... #rheumatology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
rash in association ... • Maculopapular ... Fever >38.5 2. ... Skin involvement ... withdrawal • Mild
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
(blue-purple) rash ... • Erythematous rash ... Dermatomyositis • Fever ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... 3rd Decade Skin ... Differential Diagnosis ... to: Arthritis, Fever ... #Rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... Vasculitis: • Fevers ... , mucositis • Rash ... vesicles, pustules, maculopapular ... #Rheumatology
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