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management disease dermatology differential stills treatment adultonset vasculitis aosd dermatomyositis kawasaki signs symptoms syndrome activation algorithm antimda5 antimda5dm autoimmune causes
Adult Onset Still's Disease - Yamaguchi Criteria Major criteria: - Fever >= 39C lasting >= 1 weeks
Adult Onset Still's ... : - Fever >= 39C ... weeks - Typical skin ... #Diagnosis #Major ... #Minor #Rheumatology
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... with urticarial rash ... maculopapular skin ... #Adult #onset ... #rheumatology #
Maculopapular - Diagnostic Algorithm Pathophysiology: - Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - Diagnostic ... instability - New-onset fever ... with rash - Mucocutaneous ... sulfa-drug - Skin ... #Dermatology #Rash
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Joint Pain Rash ... • Rheumatic fever ... gangrenosum • IBD ... #differential #diagnosis ... #rheumatology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Clinical triad: Fever ... Arthralgia/arthritis, Skin ... rash ± odynophagia ... management #treatment #rheumatology
Kawasaki Disease (KD) - Diagnosis and Management Summary Kawasaki Disease (KD) is the most common vasculitis of
rarely occurs in adults ... Presentation: • Fever ... Criteria - Fever ... Polymorphous rash ... KD #vasculitis #rheumatology
Adult-Onset Still's Disease (AOSD) Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's ... : High spiking fever ... maculopapular rash ... Systemic AOSD: high fever ... Disease #AOSD #rheumatology
Kawasaki Disease: Clinical Findings Diagnostic Criteria - Fever and 4/5 of the following: • Conjunctivitis • Polymorphous
Clinical Findings Diagnostic ... Criteria - Fever ... • Polymorphous rash ... - Generalized Skin ... #Diagnosis #Pathophysiology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
arthritis (sJIA) • Adult-onset ... Petechial or purpuric rash ... Histopathologic criteria ... Activation #Syndrome #Diagnosis ... #Rheumatology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
(blue-purple) rash ... • Erythematous rash ... Dermatomyositis • Fever ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
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