9 results
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
(blue-purple) rash ... • Erythematous rash ... chest (in a V-sign ... Inverse Gottron’s sign ... ulcerations • Skin
Palpable Purpura seen in Henoch Schonlein Purpura (HSP, IgA Vasculitis)

55 year old male on tuberculosis treatment
Schonlein Purpura (HSP ... , IgA Vasculitis ... ) 55 year old ... #clinical #photo ... #dermatology #skin
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings
Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
Dermatomyositis ... processes occur in the skin ... -> Heliotrope Rash ... Pathophysiology #Signs ... #Symptoms #Vasculitis
Moccasin-variety Tinea Pedis 
70 M chronic scaly feet. Over the years: rash has itched only occasionally;
Moccasin-variety Tinea ... Over the years: rash ... dermatophytes cause ... skin of inflamed ... type #clinical #photo
Henoch Schonlein Leg Rash - Palpable Purpura
Purpura: Low Platelets or Vasculitis?
45 years old, seen in our
Schonlein Leg Rash ... 45 years old, seen ... later confirmed by skin ... #clinical #photo ... #dermatology #HSP
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
- Rash: multiple ... Episcleritis Signs ... Causes: - Idiopathic ... multiforme - Dermatomyositis ... Leukocytoclastic vasculitis
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Purpura, ischemic skin ... purpura: Strong sign ... of shoulder and hip ... , mucositis • Rash ... tract, and often causes
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
(blue-purple) rash ... • Erythematous rash ... chest (in a V-sign ... Muscle atrophy may cause ... : • ILD was diagnosed
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Anti-MDA5 (RP-ILD ... ) • Anti-Mi2 (skin ... Symptoms: • Gottron rash ... ) • Shawl sign ... statins - probably caused