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dermatology rheumatology differential dermatomyositis symptoms antimda5 antimda5dm antinxp2 antinxp2dm autoimmune clinical compared comparison erythema erythemas foot heatstroke lupus maculopapular management
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
(blue-purple) rash ... with edema • Erythematous ... rash on the face ... violaceous macules and erythematous ... #dermatology #diagnosis
SKIN RASHES Skin rashes can occur from a variety of factors, including infections, heat, allergens, immune
including infections, heat ... rapid and accurate diagnosis ... fever and systemic signs ... of illness should ... petechiae; #purpura; #rash
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework Heat Cramps: • Muscle pain or spasm -
Heat Illnesses and ... Diagnosis Framework ... Rash: • Small ... → Syncope • Signs ... #diagnosis #causes
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... , Vasculitis, Purpura ... #signs #symptoms ... #diagnosis #rheumatology
Moccasin-variety Tinea Pedis 70 M chronic scaly feet. Over the years: rash has itched only occasionally;
Over the years: rash ... Diagnosis? ... dermatophytes cause ... sp. pruritic, erythematous ... skin of inflamed
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
processes occur in the skin ... -> Heliotrope Rash ... Polymyositis #PM #Diagnosis ... Pathophysiology #Signs ... #Symptoms #Vasculitis
Erythemas Summarized Erythema ab igne • A dermatosis that results from repeated exposure to heat (fires, heating
repeated exposure to heat ... of necrotizing vasculitis ... presenting with erythematous ... include: infections (HSV ... #differential #diagnosis
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
- Rash: multiple ... Episcleritis Signs ... Causes: - Idiopathic ... influenza-like illness ... Leukocytoclastic vasculitis
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... of shoulder and hip ... : Erythematous nodules ... , mucositis • Rash ... tract, and often causes
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
DM with generalized ... to have typical DM ... rash on the face ... Muscle atrophy may cause ... Dermatomyositis: • ILD
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