10 results
Acute Purpura Fulminans Skin Rash on Physical Exam 
60 year old male ITP s/p splenectomy 
1d
Skin Rash on Physical ... Exam 60 year old ... splenectomy 1d chills ... BIDMC Infectious Diseases ... #photo
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Joint Pain Rash ... infection Malar rash ... Palpable purpura ... gangrenosum • IBD ... #rashes #differential
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Arthralgia/arthritis, Skin ... rash ± odynophagia ... fraction < 20% Differential ... #management #treatment
Pigmented Purpuric Dermatoses (PPD) - Capillaritis

Group of chronic, benign, cutaneous eruptions characterized by the presence of
and increased skin ... extremities Schamberg Disease ... brown tint of the rash ... eczematous features • Mild ... Dermatoses #Dermatosis #differential
Henoch Schonlein Leg Rash - Palpable Purpura
Purpura: Low Platelets or Vasculitis?
45 years old, seen in our
Schonlein Leg Rash ... 45 years old, seen ... Tip: To differentiate ... later confirmed by skin ... #photo #dermatology
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... Disease Systemic ... maculopapular skin ... #Adult #onset #Stills ... #rheumatology #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
• Adult-onset Still ... easy bruising to purpura ... (Petechial or purpuric ... rash) • Heart, ... Syndrome #Diagnosis #Management
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
rash in association ... Skin involvement ... Resolution > 15 days Differentials ... withdrawal • Mild ... disease: symptomatic
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... permanent alopecia Differential ... arthritis, adult-onset Still ... CNS • Headache, mild ... Seizures • Strokes Skin
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
But can still have ... (blue-purple) rash ... had more severe disease ... Dermatomyositis: • ILD ... Dermatomyositis #diagnosis #management