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dermatology differential lupus sle systemic dermatomyositis vasculitis activation antimda5 antimda5dm antinxp2 antinxp2dm autoimmune classification clinical comparison dermatologic dress druginduced foot
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Joint Pain Rash ... gangrenosum • IBD ... Antiphospholipid-antibody syndrome ... #differential #diagnosis ... #rheumatology
Moccasin-variety Tinea Pedis 70 M chronic scaly feet. Over the years: rash has itched only occasionally;
Over the years: rash ... Diagnosis? ... dermatophytes cause ... sp. pruritic, erythematous ... skin of inflamed
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Associated with skin ... Treatment: • Mild ... #SLE #Summary #diagnosis ... #rheumatology # ... management
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... Demyelinating syndromes ... signs #symptoms #diagnosis ... #rheumatology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
(blue-purple) rash ... with edema • Erythematous ... rash on the face ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... Differential Diagnosis ... Non-autoimmune rheumatologic ... Seizures • Strokes Skin ... #Diagnosis #Rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Maculopapular rash ... • Goodpasture syndrome ... #dermatology #rash ... #diagnosis #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Systemic lupus erythematosus ... Petechial or purpuric rash ... systemic lupus erythematosus ... #Diagnosis #Management ... #Hematology #Rheumatology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
rash in association ... Edema in 70% of cases ... withdrawal • Mild ... SinaiBmoreIMRes #DRESS #Syndrome ... #management
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
NPSLE rare, Malar rash ... Prognosis: Usually mild ... Systemic Lupus Erythematosus ... comparison #table #rheumatology ... #diagnosis #management
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