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diagnosis rheumatology amyloid amyloidosis dermatology drugrelated exanthema hematology intertriginous lupus management mas sdrife sle symmetrical syndrome systemic
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... Fever is the main clinical ... easy bruising to purpura ... (Petechial or purpuric ... rash) • Heart,
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... 3rd Decade Skin ... CNS • Headache, mild ... Seizures • Strokes Skin ... Chronic B-cell activation
Symmetrical Drug-Related Intertriginous and Flexural Exanthema (SDRIFE) 49M +burning rash groins/buttocks (pic in next thread) x 1d.
Intertriginous and Flexural ... well-demarcated, erythematous ... , blisters, or purpura ... Washington University ID ... #clinical #photo
Amyloidosis - Summary Group of disorders associated with extracellular deposition of fibrils formed from low-molecular-weight proteins in
Clinical suspicion ... Amyloidosis Clinical ... • Periorbital purpura ... Inflammation → Macrophage ... activation → IL
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