13 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint ... Pain Rash ... Crohn's disease Palpable ... Antiphospholipid-antibody syndrome ... lesions • Discoid lupus
Palpable Purpura seen in Henoch Schonlein Purpura (HSP, IgA Vasculitis)

55 year old male on tuberculosis treatment
Palpable Purpura ... ) 55 year old ... abdominal pain, joint ... #clinical #photo ... #dermatology #skin
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Infection - Vasculitis ... Rash: - Purpura ... Rash: - Autoimmune ... Vasculitis (lupus ... cryoglobulins • Skin
Henoch Schonlein Leg Rash - Palpable Purpura
Purpura: Low Platelets or Vasculitis?
45 years old, seen in our
- Palpable Purpura ... Palpable purpura ... Palpable = vasculitis ... later confirmed by skin ... #photo #dermatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
surfaces of the joints ... • Petechiae, Palpable ... Maculopapular rash ... • Goodpasture syndrome ... #dermatology #rash
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... , Vasculitis, Purpura ... Demyelinating syndromes ... erythematosus #signs
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
vesicular eruption - Joints ... mucositis - Rash ... such as systemic lupus ... sign of cutaneous ... -> causing palpable
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
sign of cutaneous ... , mucositis • Rash ... ) • Palpable purpura ... , joint & gut involvement ... ) • Palpable purpura
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- Skin ulcers ... Clinical triad of Palpable ... infection • Autoimmune ... reticularis & skin ... (e.g. systemic lupus
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... disease • Non-autoimmune ... deficiencies • Autoimmune ... Arthritis: • Joint ... arthropathy • 90% joints