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diagnosis rheumatology differential dermatology classification erythematosus hematology lupus pain signs symptoms systemic arthropathies arthropathy behcet conditions cryoglobulinemia cryoglobulins cutaneous dermatologic
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Associated with Joint ... Pain Rash ... infection Malar rash ... Sarcoidosis • GPA ... Antiphospholipid-antibody syndrome
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... surfaces of the joints ... Maculopapular rash ... • Goodpasture syndrome ... #dermatology #rash
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... Splenomegaly - CTD (SLE ... Kasabach-Merritt syndrome ... - GPA - EGPA ... Associated - SLE
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
vesicular eruption - Joints ... mucositis - Rash ... • Cogan Syndrome ... • ANCA (Dx: GPA ... , and SLE) • Urinalysis
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
Secondary: CTD: SLE ... Petechiae, Palpable purpura ... - GPA Cutaneous ... : • Behcet Disease ... • Cogan syndrome
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Associated with Joint ... Vasculitis (e.g. ... Scleroderma Thickened skin ... Heberden's nodes (DIP joints ... Bouchard's nodes (PIP joints
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
, such as SLE, atherosclerotic ... vesicular eruption • Joints ... , mucositis • Rash ... , joint & gut involvement ... • Cogan syndrome
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... , Vasculitis, Purpura ... Demyelinating syndromes ... pain (20%) Renal disease
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- Skin ulcers ... • Autoimmune diseases ... : - 10% SLE or ... reticularis & skin ... - GPA, EGPA, microscopic
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
Differential Diagnosis Algorithm ... arthritis - (Reiter’s syndrome ... arthritis - with the skin ... Erythematosus (SLE ... like “butterfly rash
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