15 results
Non-HCV infectious mixed cryoglobulinemia vasculitis - Diagnosis, causes and management - French Vasculitis Study Group

< 5%
vasculitis Clinical ... manifestations - Skin ... involvement with purpura ... with refractory disease ... #Diagnosis #Management
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Rarely dominate the clinical ... Maculopapular rash ... • Mixed cryoglobulinemia ... • Goodpasture syndrome ... #dermatology #rash
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- Skin ulcers ... Syndrome: • Clinical ... • Autoimmune diseases ... reticularis & skin ... Labs/Diagnosis:
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... ANCA +MPO) • Cryoglobulinemic ... mucositis - Rash ... • Cogan Syndrome ... Low levels mixed cryoglobulinemia
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... lesions, palpable purpura ... response to local skin ... (Clinical Dx). ... #diagnosis #management
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
- Differential Diagnosis ... Vasculitis Differential Diagnosis ... , mucositis • Rash ... / ANCA + MPO) Cryoglobulinemic ... #Differential #Diagnosis
Moccasin-variety Tinea Pedis 
70 M chronic scaly feet. Over the years: rash has itched only occasionally;
Over the years: rash ... Diagnosis? ... skin of inflamed ... Variety #type #clinical ... #photo #foot #dermatology
Capnocytophaga Canimorsus Skin Rash

40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
+purpuric rash → ... purpura fulminans ... the key to the diagnosis ... University Infectious Diseases ... #clinical #photo
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Cryofibrinogenemia Clinical ... necrosis • Purpura ... Cryofibrinogenemia Diagnosis ... : • + Clinical ... Antiphospholipid syndrome
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... Sjögrens (15%) Skin ... , Vasculitis, Purpura ... Demyelinating syndromes ... pain (20%) Renal disease